1. Which of these is NOT true about the active site of an enzyme? a.) It is comp

ID: 56204 • Letter: 1

Question

1. Which of these is NOT true about the active site of an enzyme?

a.) It is composed of distinct amino acids that perform catalytic activities

b.) It often has a prosthetic group depending on the enzyme

c.) It is formed by the folding of the protein

d.) It is the site of binding of a competitive inhibitor

e.) It will always be affected by changes in the primary structure of the protein

2. Which is NOT true about the Km of an enzyme:

a.) is calculated as half of the maximal velocity of an enzyme

b.) is a hypothetical number that can only be predicted using experimental data

c.) is negatively affected by a competitive inhibitor

d.) is a measure of how tightly an enzyme binds to its substrate

e.) all of the above are true

3.Which is NOT true about Vmax:

a.) is the maximal velocity at which an enzyme can function

b.) is reduced by a non-competitive inhibitor

c.) is determined on a Lineweaver-Burke plot by taking the reciprocal of the y-intercept

d.) is low for an enzyme with a low Km and high substrate affinity

e.) can be determined by multiplying the Km by 2

1. e. It will always be affected by changes in the primary structure of the protein.

2. c. is negatively afected by a competitive inhibitor. Since the affinity of the substrate for the enzyme would decrease, the Km would be higher.

3. d.) is low for an enzyme with a low Km and high substrate affinity.

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