The graph at left (modified from Kraemer, 1997. Proc. Natl. Acad. Sci. (USA) 94:

Question

The graph at left (modified from Kraemer, 1997. Proc. Natl. Acad. Sci. (USA) 94: 11–14) depicts the age of onset of skin cancers in patients with or without XP, where the cumulative percentage of skin cancer is plotted against age. The non-XP curve is based on 29,757 cancers surveyed by the National Cancer Institute, and the curve representing those with XP is based on 63 skin cancers from the Xeroderma Pigmentosum Registry.

Part A

Based on the graph, which of the following statements are true?

Select all that apply.

XP individuals almost always develop skin cancer by age 40. Individuals with XP are more likely to develop skin cancer in their youth than non-XP individuals. For non-XP individuals, the chance of skin cancer increases as they age. By age 20, approximately 80% of the XP population has skin cancer. At all ages, the non-XP individuals have half the rate of skin cancer as individuals with XP.

Explanation / Answer

These are true-

Individuals with XP are more likely to develop skin cancer in their youth than non-XP individuals. Because its more that 50% before 20 years of age.

For non-XP individuals, the chance of skin cancer increases as they age. The graph is increasing with age showing chances increase with age and not so drastic as in XP.

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