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Under cellular conditions (37 C), what is the actual free energy for the reactio

ID: 555073 • Letter: U

Question

Under cellular conditions (37 C), what is the actual free energy for the reaction shown below when the ratio of glucose-6-phosphate to fructose-6-phosphate is 0.8:0.2?
glucose-6-phosphate -> fructose-6-phosphate
Standard Gibbs Free Energy change = 1.7 kJ/mol. Under cellular conditions (37 C), what is the actual free energy for the reaction shown below when the ratio of glucose-6-phosphate to fructose-6-phosphate is 0.8:0.2?
glucose-6-phosphate -> fructose-6-phosphate
Standard Gibbs Free Energy change = 1.7 kJ/mol.
glucose-6-phosphate -> fructose-6-phosphate
Standard Gibbs Free Energy change = 1.7 kJ/mol.

Explanation / Answer

Q = Products/Reactants

Q = 0.2/0.8 = 0.25

then

dG = dG° + RT*ln(Q)

dG° = 1.7 kJ/mol = 1700 J/mol

dG = 1700 + 8.314*(37+273) * ln(0.25)

dG = -1872.95 J/mol

dG = -1.87 kJ/mol, this is favouring forward direction