In the assigned article, \"The Saltshakers Curse\", how does the application of

Question

In the assigned article, "The Saltshakers Curse", how does the application of evolutionary theory expain the link betwen salt and hyperextension in modern African Americans? In other words how does understanding evoluion (like fitness and natural selection) help us explain why modern African Americans experience such high levels of hypertension and other related health issues?) Your answer should be about 3-5 sentences.

Article link:

https://sacct.csus.edu/bbcswebdav/pid-2220597-dt-content-rid-8019685_1/courses/2158-ANTH1SH-MASTER/02_Saltshakers%20Curse.pdf

Explanation / Answer

Ans.) African Americans have exceptionally high rates of hypertension and hypertension related complications. It is commonly reported that the blood pressure lowering efficacy of renin angiotensin system (RAS) inhibitors is attenuated in African Americans due to a greater likelihood of having a low renin profile. Therefore these agents are often not recommended as initial therapy in African Americans with hypertension. However, the high prevalence of comorbid conditions, such as diabetes, cardiovascular and chronic kidney disease makes treatment with RAS inhibitors more compelling. Despite lower circulating renin levels and a less significant fall in blood pressure in response to RAS inhibitors in African Americans, numerous clinical trials support the efficacy of RAS inhibitors to improve clinical outcomes in this population, especially in those with hypertension and risk factors for cardiovascular and related diseases.

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