Determine which type of regulation best fits each description. The four types to

Question

Determine which type of regulation best fits each description.

The four types to chose from for each statement are

Allosteric regulation, Isozymes, Covalent Modification, and Proteolytic Activation

1) Is based on weak interactions between metabolic intermediates and the enzyme.

2) Uses enzymes with slightly different primary structures to provide the cell with different kinetic parameters for the same reaction.

3) Uses positive heterotropic effectors to increase enzyme activity.

4) Often uses kinases and phosphatases.

5) Uses negative heterotropic effectors to reduce enzyme activity.

6) Involves an equilibrium in which subunits are shifted between the T and R states based on the presence and absence of effectors.

7) Involves cleavage of the peptide backbone.

8) Involves reversibly adding and removing a functional group from the side-chains of amino acid residues.

Explanation / Answer

Ans.1) Is based on weak interactions between metabolic intermediates and the enzyme - Covalent Modification
2) Uses enzymes with slightly different primary structures to provide the cell with different kinetic parameters for the same reaction - Isozymes
3) Uses positive heterotropic effectors to increase enzyme activity - Allosteric regulation
4) Often uses kinases and phosphatases - Proteolytic Activation
5) Uses negative heterotropic effectors to reduce enzyme activity - Allosteric regulation
6) Involves an equilibrium in which subunits are shifted between the T and R states based on the presence and absence of effectors - Allosteric regulation
7) Involves cleavage of the peptide backbone - Proteolytic Activation
8) Involves reversibly adding and removing a functional group from the side-chains of amino acid residues - Proteolytic Activation

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