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1.) The conversion of pyruvate to lactate by lactate dehydrogenase (LDH) is acco

ID: 547300 • Letter: 1

Question

1.) The conversion of pyruvate to lactate by lactate dehydrogenase (LDH) is accompanied by the consumption of

(chose one)

a. ATP

b. ADP

c. NAD+

d. NADH

2.)Which is the best explanation for the role of lactate dehydrogenase in efficient anaerobic metabolism?

(chose one)

a. regenerate pyruvate from lactate so muscles can convert the pyruvate to glucose via gluconeogenesis

b. generate lactate as an alternative energy source for muscles

c. regenerate NAD+ to allow glycolysis to continue

d. Use NADH to prevent inhibition of hexokinase activity

Explanation / Answer

The answer is d

The conversion of pyruvate to lactate by lactate dehydrogenase (LDH) is accompanied by the consumption of NADH

pyruvate reduces to lactate whereas NADH oxidises to NAD+ during the conversion