1. Which of the following statements about genomes isfalse? a. most of the human

Question

1. Which of the following statements about genomes isfalse? a. most of the human genome concsists of coding DNA b. Genes make up most of the DNA of prokaryotes c. Genomes show a general trend of increasing complexity withcomplexity of organism d. the human genome contains several genes of bacterialorigin e. eukaryotes generally have far lower gene density thanprokaryotes 2. Candidate open reading frames of a genome are identified bysearching for a. a promoter b. a start codon "in frame" with a stop codon c. introns and exons d. a start codon e. all of the above 3. In a sequenced genome, candidate protein-encoding genes areidentified by searching for a. SNPs b. ESTs c. RFLPs d. STRs e. ORFs 4. The human genome contains approximately ------ genes a. 20,000 b. 100,000 c. 80,000 d. 10,000 e. 40,000 1. Which of the following statements about genomes isfalse? a. most of the human genome concsists of coding DNA b. Genes make up most of the DNA of prokaryotes c. Genomes show a general trend of increasing complexity withcomplexity of organism d. the human genome contains several genes of bacterialorigin e. eukaryotes generally have far lower gene density thanprokaryotes 2. Candidate open reading frames of a genome are identified bysearching for a. a promoter b. a start codon "in frame" with a stop codon c. introns and exons d. a start codon e. all of the above 3. In a sequenced genome, candidate protein-encoding genes areidentified by searching for a. SNPs b. ESTs c. RFLPs d. STRs e. ORFs 4. The human genome contains approximately ------ genes a. 20,000 b. 100,000 c. 80,000 d. 10,000 e. 40,000

Explanation / Answer

1. a: most of it is non-coding 2. a: first an enzyme identifies promoters and binds to themand then polymerase finds the downstream AUG start codon 3. b: you could probe with Expressed-Sequence tags andmicroarray...you get the est s from transcribed mRNAs 4. a: 24,000 ok, that was fun, bye

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