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Graded Homework Set 7 8 pts due first 5 min of rec 10/16/17 name recitation sect

ID: 540038 • Letter: G

Question

Graded Homework Set 7 8 pts due first 5 min of rec 10/16/17 name recitation section The rxn below shows one step in the catabolic pathway for the amino acid threonine OH NAD NADH H NH3 threonine dehydrogenase NH L-threonine 2-amino-3-ketobutyrate 1. Please label the reactants and products as oxidized form, reduced form, higher energy form and lower energy form. 2. Is NAD an enzyme? Please explain. 3. What general type of process happens in a catabolic pathway? 4. Besides catabolism, what are the two other major processes that together constitute "metabolism"? Please define each of them 5. A chiral carbon is a carbon atom that has bonds to 6. Draw the implied carbon and hydrogen atoms on the line angle structures above and circle all of the chiral carbon atoms in the structures. L-threonine has how many stereoisomers (arrangements)? 7. What is the role of threonine dehydrogenase? Would you expect it to work equally well with any stereoisomer of threonine? Explain

Explanation / Answer

1. L-threonine is reduced form(since it has more elctrons. 2- amino-3--ketobutyrate is a oxidised form.

NAD+ id low energy form and NADH + H+ is a high energy form.

2. NAD+ is not an enzyme. but it acts as a cofactor or coenzyme. t enhanecs the actvity of the enzyme. they stabilize the transition states. NAD acts as a hydrogen acceptor. Because of the positive charge on the nitrogen atom in the nicotinamide ring, the oxidized form of this important redox reagent is often depicted as NAD+. In cells, most oxidations are accomplished by the removal of hydrogen atoms. NAD coenzyme plays a crucial role in this. Each molecule of NAD+ can acquire two electrons; that is, be reduced by two electrons. However, only one proton accompanies the reduction. The other proton produced as two hydrogen atoms are removed from the molecule being oxidized is liberated into the surrounding medium.

3. catabolim is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy.Catabolism breaks down large molecules (such as polysaccharides, lipids, nucleic acids and proteins) into smaller units (such as monosaccharides, fatty acids, nucleotides, and amino acids,ect) with the help of enzymes.

4. metabolism has also Anabolism Anabolism is the set of constructive metabolic processes where the energy released by catabolism is used to synthesize complex molecules) excreation( flushing out of waste materials.