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In the first reaction of glycolysis (reaction (3) below), glucose reacts with a

ID: 538171 • Letter: I

Question

In the first reaction of glycolysis (reaction (3) below), glucose reacts with a molecule of adenosine triphosphate (ATP), yielding a molecule of glucose 6-phosphate (G6P) and a molecule of adenosine diphosphate (ADP). Essentially, a phosphate group (usually abbreviated "P_i" for "inorganic phosphate") is transferred from ATP to glucose. This reaction has a negative Delta G in cells. (3) Glucose + ATP rightarrow Glucose 6-phosphate + ADP Sometimes, it's useful to think of reactions of this sort as separate "half reactions." Though the half reactions don't occur on their own, the net of the two half reactions describes the reaction that does occur. One of the half reactions for reaction (3) is: (4) ATP + H2_O rightarrow ADP + P_i Predict what the second half reaction is for reaction (3) Glucose + P_i rightarrow Glucose 6-phosphate + H_2 O ATP + H_2 O rightarrow Glucose 6-phosphate Glucose rightarrow Glucose 6-phosphate Glucose rightarrow ATP + P_i + H_2 O

Explanation / Answer

overall reaction is Glucose+ATP---->G-6P+ADP (3)

ATP+H2O ---------->ADP+Pi (4)

Eq.3= Eq.4+ required equation

required equation= Eq.3-Eq.4= Glucose+ATP-ATP-H2O ------------->G6P+ADP-ADP-PI

Glucose + PI ------->G-6-P+ H2O is the required reaction ( A is the correct answer)

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