1. Which of the following ranks as one of the most important factors governing d

Question

1. Which of the following ranks as one of the most important factors governing drug disposition?

a. Bioavailability b. Volume of distribution c. Clearance d. Elimination half-life (t1/2) e. All of the above

2.. Carbon monoxide might be present in an individual’s blood from which of the following?

a. The metabolism of dihalomethanes such as methylene chloride b. Cigarette smoke c. The exhaust from internal combustion machines d. Malfunctioning heating and ventilation systems e. All of the above

3. Acetaminophen toxicity may lead to __________________.

a.     renal failure b.     blindness c.     liver failure d.     paralysis

Explanation / Answer

1. Answer: (e) All of the above

All the given factors such as bioavailabilty, volume distribution, elimination of halflife and clearance are important factors for drug disposition.

2. Answer: (e) All the above

The metabolism of dihalomethanes such as methylene chloride, smoking, The exhaust from internal combustion machines and Malfunctioning heating and ventilation systems, all of the above factors are responsible for Carbon monoxide might be present in an individual’s blood.

3. Answer: (c) Liver failure

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