we want you to write about 5 different ways nanoparticles could be used to diagn

Question

we want you to write about 5 different ways nanoparticles could be used to diagnose or treat your disease of interest. For each case, think about… What do you want your nanoparticles to accomplish? What types of biological barriers do you need to overcome? What materials would you use and why? What sorts of physical characteristics are important to consider when designing nanoparticles for your disease application? Do you need to release a drug, and if so, should the drug be released slowly or quickly? What patients would benefit from this treatment? If these nanoparticles only treat a sub-set of patients, how could you change your design to reach more patients? MY DISEASE IS MALARIA PLEASE I WANT THE ANSWER FASTER.

Explanation / Answer

Nanoparticle and Malaria.

Gold nanoparticles are used for calorimetric diagnosis of malaria.

Curcumin based nanoparticles are proved to be anti malarial drugs

Low availability of drug is enhanced

Polymers are used to mimic red blood cells where the parasite binds.

Sustained drug release is enabled by encapsulation.

Biological barriers to overcome are - skin, nasal secretion, mucosa, small intestine and blood brain barrier.

Physical characteristics - Size of nanoparticle and temperature stability.

Materials used - Non toxic materials to cell such as synthetic polymers, peptides, lipids, organic metals can be used.

Nanoparticles treat all the patients with malaria

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