1.An insertion of two nucleotides into a gene: A. has no effect on the amino aci
ID: 52466 • Letter: 1
Question
1.An insertion of two nucleotides into a gene:
A.
has no effect on the amino acid sequence of the encoded protein
B.
introduces a premature stop codon into the mRNA
C.
changes in an amino acid in the encoded sequence
D.
alters the reading frame of the mRNA
2. A mutation involving the deletion of three consecutive nucleotides from a gene intron region would result in a protein that is:
A.
Exactly identical to the original protein in structure and function
B.
The same amino acid sequence in the N-terminus region, and completely different after the mutation region
C.
Completely non-functional
D.
One amino acid shorter and may or may not be functional
3. During elongation, which site in the ribosome represents the location where a tRNA is being released?
A.
the large ribosomal subunit
B.
E site
C.
P site
D.
A site
A.
has no effect on the amino acid sequence of the encoded protein
B.
introduces a premature stop codon into the mRNA
C.
changes in an amino acid in the encoded sequence
D.
alters the reading frame of the mRNA
Explanation / Answer
1. D. Alters the reading frame of mRNA.
Insertion mutation (occurs due to the insertion of nucleotides to the gene sequence) alters the reading frame of mRNA beyond the region of insertion. This causes misreading of all the gene sequence.
2. A. Exactly identical to the original protein in structure and function
Introns are non-coding regions of RNA.
3. B. E site (Exit site)
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