(2 Points) Certain drugs are commonly used to study mitochondrial respiration. T

Question

(2 Points) Certain drugs are commonly used to study mitochondrial respiration. These drugs include rotenone, oligomycin, and the mitochondrial uncoupler dinitrophenol. Rotenone inhibits the transfer of electrons from Complex Ito ubiquinone, oligomycin inhibits Complex V/ATP Synthase by preventing the re-entry of protons into the matrix, and dinitrophenol leads to the uncoupling of oxidation from phosphorylation of ADP (meaning that less ATP is produced). If you were interested in studying the ATP production through glycolysis only, which of these inhibitors would be most useful? Why?

Explanation / Answer

Answe:

Glycolysis is the catabolic process, involves the break down of the glucose molecules into pyruvate, during this process two ATP are formed by the end of the glycolysis. The drugs that are mentioned in question blocks the pathway in the electron transport chain but not in the Glycolysis, these inhibitors doesnt have any influence on the gllycolysis.

Cellular respiration involve there stages:

1) Glycolysis

2) Citric acid cycle

3) Electron transport chain.

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