3. A particular gene has two alleles in a population (A and a). If the frequency

Question

3. A particular gene has two alleles in a population (A and a). If the frequency of the A allele equals 0.3, what is the frequency of homozygous aa individuals in the population?

0.84

0.70

0.49

0.42

0.09

4. Which of the following are characteristics of genes for continuously variable traits?

Genes have two alleles, one contributing, one not contributing

Genes have multiple alleles that have different contributions to the phenotype

All contributing alleles of the different genes contribute equally to the phenotype

The contributing alleles of the different genes do not contribute equally to the phenotype

Answers (2) and (4)

Answers (1) and (3)

5. Lesch-Nyhan syndrome is an autosomal recessive human disease involving a single gene (LN). The wild-type gene is completely dominant to the recessive gene (ln). The frequency of individuals with Lesch-Nyhan disease is one in 4,000. What is the frequency of heterozygote carriers of the recessive mutations?

0.00025

0.0158

0.031

0.05

Please show worka dn explain!

Explanation / Answer

P +q = 1

P = A, q = a

q = 0.3, so p + q = 1

p + 0.3 = 1

p = 0.7

p2 = 0.49

2. Answer 2 and 4 – If genes do not participate equally then there will be a misbalanced in and if there will be a misbalance, there phenotypes will change automatically. If this changed phenotype goes in next generation and different characters will be expressed which will be classified as variation.

3. Disease has the incidence of 1 in 4000 individuals = q2 , q = root of 1/4000 = 0.01

P + q = 1, p + 0.01 = 1

P = 0.99

For heterozygote = 2pq = 2 X 0.01 X 0.99 =0.198.

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