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Score: Sorry, you are Incorrect. Answer(s): (Your response(s) are shown.) For th

ID: 51701 • Letter: S

Question

Score:
Sorry, you are Incorrect.

Answer(s): (Your response(s) are shown.)

For the uncoupled and coupled reactions

glucose + phosphate glucose-6-phosphate, G°' = +13.8 kJ/mol
glucose + ATP glucose-6-phosphate + ADP, G°' = -16.7 kJ/mol

By how much does coupling to ATP increase the apparent equilibrium constant for the formation of glucose-6-phosphate? Given R = 8.315 J/mol · K. T = 298 K.

, G°' = -16.7 kJ/mol

By how much does coupling to ATP increase the apparent equilibrium constant for the formation of glucose-6-phosphate? Given R = 8.315 J/mol · K. T = 298 K.

2.2 × 108 times 4.5 × 10-6 times 2.2 × 105 times

Explanation / Answer

Coupling glucose to phosphate directly produces glucose-6-phosphate with Gibbs free energy change +13.8 kJ/mol. The production of the same product coupling glucose with ATP occurs with Gibbs free energy chage -16.7 kJ/mol. The difference in the Gibbs free energy change for both the reactions is -16.7 kJ/mol. Thus, coupling to ATP has increased the apparent equilibrium constant by releasing 16.7 kJ/mol of energy. It is nearly an increase of 1.2 times that of coupling with phosphate (13.8 kJ/mol).

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