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For Claisen condensation reaction using methyl propanoate, NAOCH3, is the ideal

ID: 515200 • Letter: F

Question

For Claisen condensation reaction using methyl propanoate, NAOCH3, is the ideal base. Why is it important to use NaOCH3 and not NaOCH2CH3

2) For a Claisen condensation reaction using methyl propanoate, NaOCH3 is the ideal base. Why is it important to use NaOCH 3 and not NaOCH2CH3? (0.5 pts) a) NaOCH3 is a stronger base than NaOCH2CH3 and this reaction requires a stronger base b) NaOCH3 is a weaker base than NaOCH2CH3 and this reaction requires a weaker base c) Transesterification can occur and will result in a mixture of products d) The choice of base is not important

Explanation / Answer

Option C) is correct. Transesterification will occur which will result in a mixture of product.

For this reaction we need strong base and sodiumethoxide is a better base than sodium methoxide

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