apling Learning Map macrmillan learning The following paragraphs describe the fi
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apling Learning Map macrmillan learning The following paragraphs describe the first three reactions of a metabolic pathway. Fill in the blanks by moving words to the appropriate blanks. Note that a single red X will appear if you answer any of the blanks incorrectly. Feedback will be placed next to a blank that is incorrectly filled Not all the terms wil be placed In reaction 1 of the Krebs cycle, acetyl-CoA formed in the pyruvate dehydrogenase reaction condenses with the four-carbon compound to form with the elimination of coenzyme A. Since the product has three carboxyl groups, this pathway is referred to as the cycle. In reaction 2 of the Krebs cycle, this product then undergoes to form The enzyme is called aconitase because the compound cis-aconitate is a(n) of the reaction Reaction 3 eliminates CO2 to form the 5-carbon dicarboxylic acid Oxidation also occurs, with electrons transferred from the substrate to Consequently this reaction is an oxidative decarboxylation a ketoglutarate Condensation intermediate NAD oxaloacetate succinate FAD isocitrate citrate tricarboxylic acid isomerization product Previn Give DR View solution Check Answer E Next AIFxitExplanation / Answer
In Reaction 1 of the Krebs cycle, acetyl- CoA formed in the pyruvate dehydrogenase reaction condenses with the four – carbon compound Oxaloacetate to form Citrate with the elimination of coenzyme A.
Since the product has three carboxyl groups, this pathway is referred to as the tricarboxylic acid cycle.
In the reaction 2 of the Krebs cycle, this product then undergoes isomerization to form isocitrate.
The enzyme is called aconitase because the compound cis-aconitate is a(n) intermediate of the reaction.
Reaction 3 eliminates C02 to form the 5-carbon dicarboxylic acid -ketoglutarate. Oxidation also occurs, with electrons transferred from the substrate to product. Consequently this reaction is an oxidative decarboxylation.
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