At absolute zero, how would you maintain temperature? Briefly explain. Use equat

Question

At absolute zero, how would you maintain temperature? Briefly explain. Use equations, figures and/or diagrams to support you answer. reference Fenn What you should have learned in Thermodynamics! Given Delta G_binding = Delta H - T Delta S. Where Delta G_binding represents the binding sites in a system. Explain, in your own words, whether the number binding of sites will increase or decrease as a function of enthalpy or entropy. Explain how this would be important in medicinal chemistry or specifically how a drug would function in vivo/in vitro.

Explanation / Answer

2) If you conserve the energy i.e) without letting in or out any energy we can actual maintain
close to absolute temperature. The system should not come in contact with the surroundings,
which is more like no heat transfer situation.
This is more like hypothesis with a contradictory statement so try to figure out with the following
   explanation,
    Entropy at absolute temperature is minimal (negligible) therefore taken as 0 according to second
law of thermodynamics
S = Q / T
There will be no heat transfer in this case, [ Q = 0]
     S = 0 / T = 0
Since we are able to prove this we can say that absolute temperature can be maintained when there
   is no heat transfer.
3) Gbinding = H - TS
Number of binding sites decrease with increase in entropy and decrease in enthalpy respectively
As entropy increases disorder increases and the number of free binding sites.
  The drug potential can be estimated using all these factors. A drug with good binding energy
   can be effective one.
  
  



  

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