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e www.saplinglearning.com/ibiscms/mod ibis/view.php?id 3215429 017 10:55 PM A 8.3/10 Gr Print calculator Periodic Table of 6 amino acids, or both glucogenic and ketogenic amino acids. Click here to view a table of amino acids. Note: If you answer any part of this question incorrectly, a single red X will appear indicating that one or more of the phrases are sorted incorrectly. Both Ketogenic Glucogenic glutamine valine leucine tyrosine directly converted converted acid can be catabolized to acetyl-CoA intermediates to release free energyExplanation / Answer
Ans. I. Glucogenic: Glutamine, Valine
II. Ketogenic: Leucine, directly converted to acetyl-CoA.
III. Both: Tyrosine, Converted to citric acid intermediates, can be catabolized to relased energy
II. An amino acid producing acetyl-CoA or Acetoacetyl-CoA is called ketogenic amino acid because as a citric acid cycle intermediates (Acetoacetyl CoA can be converted to Acetyl-CoA) it can further produce fatty acids or ketone bodies. Leucine and Lysine are the only amino acids acting as ketogenic amino acid in true sense.
The amino acids namely Alanine, Arginine, Asparagine, Aspartate, Cysteine, Glutamate, Glycine, Histidine, Methionine, Proline, Serine, and Valine give rise to succinyl-CoA. These amino acids, with respect to the fact that they produce succinyl-CoA, are glycogenic amino acids. An amino acid producing succinyl-CoA (or, a-ketoglutarate, fumarate, oxaloacetate and pyruvate) are called glucogenic amino acids because these citric acid cycle intermediates can further be used to synthesize glucose. During catabolism, the carbon skeletal of these amino acids may be converted to pyruvate or TCA intermediates for the purpose of glycogenesis. The catabolized intermediates may also be used to energy production, if needed.
Five amino acid can act as both glucogenic and ketogenic amino acid depending on the citric acid cycle intermediate they form. Example includes Tyrosine, Isoleucine, Tryptophan, Phenylalanine and threonine.
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