Thyroxin(3)-Receptor-alpha-1 (T3R1), T3R2 and T3R are thyroxin receptor (TR) iso

Question

Thyroxin(3)-Receptor-alpha-1 (T3R1), T3R2 and T3R are thyroxin receptor (TR) isoforms that are found in different tissues of the body. Except for a few differentiated cells in the body (e.g., T-cells), all cells have a full complement of genomic DNA. These three receptors are expressed mutually exclusively in different cells, yet they come from the same open reading frame. Thus, different cells express the appropriate isoform using the gene expression mechanism of ________________.

Explanation / Answer

c. alternative splicing

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