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Rank each of the following compounds in decreasing order of reactivity towards F

ID: 497282 • Letter: R

Question

Rank each of the following compounds in decreasing order of reactivity towards Friedel-Crafts alkylation.

Most reactive = 1; if a compound will not react, rank it as "non" rather than assigning a numerical value.

Compound A: iodobenzene _____1234non

Compound B: toluene _____1234non

Compound C: acetophenone _____1234non

Compound D: fluorobenzene _____1234non

Rank each of the following compounds in decreasing order of reactivity towards Friedel-Crafts alkylation Most reactive -1; if a compound will not react, rank it as "non" rather than assigning a numerical value Compound A: iodobenzene 2 Compound B toluene 1 Compound C acetophenone 3 Compound D: fluorobenzene 4 3 tem attempts remaining Submit Answer Try Another Version

Explanation / Answer

Toluene 1 . - In toluene weakly activating methyl group is present. Activating group facilitate the fridele craft alkylaton (it is electrophilc substitution reaction).

Iodo benzene 2 - In iodo benzene iodine is weakly deactivating group. Iodine electronegativity is less than fluorine. deactivating capacity is less comparaded to fluorine.

Fluoro benzene 3 - In fluoro benzene fluorine is also weakly deactiving group. Frildel craft alkylation is slow.

Acetophenone 4 - In acetophenone moderatlely deactivating group carbonyl is present. Fridel craft alkylation is vey slow.

Ring activating groups facilitate fridel craft alkylation why because fridel craft alklyation is electrophilic substitution reaction.