Please help me solve this using the table attached. Big thanks in advance!! TABL

Question

Please help me solve this using the table attached. Big thanks in advance!! TABLE 5.1 Properties of the common amino acids found in proteins Abbreviations 1 pKa of 3-letter codes pKa of pKa of Ionizing Residue Mass Occurrence a cooH Group" a-NHS Group" Side Chain 2.3 (daltons) in Proteins (m 9.7 2.2 A Ala. Arginine R Arg Asparagine Asn 71.08 9.0 8.7 12.5 2.0 Aspartic acid Asp 156.20 8.8 5.00 2.1 C, Cys 114.11 9.8 Glutamine Q Gln 1.8 3.9 4.2 115.09 10.8 Glutamic acid E.Glu 2.2 8.3 5.9 9.1 103.14 2.2 1.3 9.7 Histidine 128.14 H.His 4.2 3.7 Isoleucine I, lo 1.8 129.12 9.2 6.6 57.06 LLou 6.00 Lysine, 9.7 7.9 137.15 Methionine Lys M. Met 2.2 2.4 113.17 Phenylalanine F Phe 9.0 2.3 5.5 113.17 10.0 1.8 P, Pro Serine 128.18 9.1 2.0 S, Ser 5.5 131.21 2.2 Tryptophan W Trp 147.18 9.2 2.6 97.12 4.0 10.4 2.4 9.4 87.08 2.2 V Val 101.11 9.1 5.8 2.3 186.21 10.1 9.6 5.6 163.18 1.5 99.14 3.5 7.2

Explanation / Answer

5.

Rate enhancement = Catalayzed rate constant/ Uncatalyzed rate constant

                               = 106 / 0.1386 = 7.215x106

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