Which to the following regulate oxidative phosphorylation under hypoxic conditio
ID: 486383 • Letter: W
Question
Which to the following regulate oxidative phosphorylation under hypoxic conditions? Pyruvate dehydrogenase (PDH) kinase phosphorylates PDH, inactivating it and reducing the availability of electron earners to the electron transport chain. High pyruvate concentrations increase pH above 6.8, stabilizing the inhibitory |F_1 dimer and preventing ATP hydrolysis HlF-1 replaces a subunit of Complex IV of the electron transport chain with a subunit that is more efficient under hypoxic conditions the protein inhibitor IF_1 binds two ATP synthase molecules and inhibits their ATPase activity ATP synthase converts ATP to ADP. raising (ADP] to increase the rate of oxidative phosphorylationExplanation / Answer
These are true:
Pyruvate dehydrogenase (PHD) kinase... TRUE
The protein inhibito IF1, .... TRUE
HIF-1 replaces a subunit... TRUE
FALSE:
High piruvate concentrations --> FALSE, the pH will not stabilize the inhibitin
ATP synthase converts ATP to ADP --> False, this is nte the case, i.e. it is reversed
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.