EXPERIMENT 19 Rolaids An Analysis of Commercial Antacids Seltzer OBJECTIVES: Det

Question

EXPERIMENT 19 Rolaids An Analysis of Commercial Antacids Seltzer OBJECTIVES: Determine the per gram neutralizing ability of a commercial antacid Determine the per gram neutralizing ability of sodium bicarbonate Compare the effectiveness ofseveral antacids. INTRODUCTION: "How do you spell relief?" The parietal cells in the stomach secrete sufficient hydrochloric acid to normally keep the acidity at about 0.10 The flow of HCI increases when food enters the stomach and so acidity increases when you eat or drink. If overstimulation of gastric juices builds the concentration up too much, heartburn or indigestion often results. Sodium bicarbonate (NaHCO in baking soda) has historically been used to try to relieve this condition. Today we have a number of commercial products which purport to neutralize (or buffer) excess stomach acid. Television commercials claiming greater effectiveness in neutralizing acid are familiar. Rolaids claims to consume 47 times its weight in excess stomach acid. Tums claims to have one third more neutralizing power than other antacids. In this lab, we will compare acid- neutralizing capabilities for ourselves. Several types of commercial antacids will be tested and the results will be shared in class. Keep in mind that tablets may also contain flavors, sweeteners, binders, fillers, antifoam agents, pain relievers, etc. In this experiment, the tablets will be analyzed only for their ability to neutralize acids. The active ingredient in antacids varies with the brand. The table below lists active ingredients in several brands. COMMERCIAL ANTACIDS' MAJOR ACTTVE INGREDIENTS Brand Active Agent Milk of Magnesia Mg(OH)2 Rolaids Alka-Seltzer II NaHCO3 and KH Maalox Mg(OH)2 and AICOH)3 Al(OH)3 Gaviscon The H (actually H30) from acids are neutralized by these agents as illustrated below: insoluble carbonates: CaCO,(s) 2 H (aq) Ca (aq) H2O() con(g soluble bicarbonates: Hco3 (aq) H (aq) H20 (l) co2 (g)

Explanation / Answer

The major ingredients in the "Alka Seltzer 2" tablet is :

Sodium bicarbonate and potassium bicarbonate.

When bicaronates react with an acid they release CO2 gas.

The chemical reaction is as shown below:

NaHCO3(aq) + HCl(aq) -----------------> NaCl (aq) + H2O + CO2 (g)

The main ingredient in milk of magnesia is magnesium hydroxide.

When Mg(OH)2 reacts with an acid it a salt and water.

It is as shown below:

Mg(OH)2 (aq) + 2HCl (aq) --------------> MgCl2 (aq) + 2H2O

HENCE BOTH ARE NOT SAME.

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