Facts about ribosomes Indicate whether each of the following statements about ri

Question

Facts about ribosomes

Indicate whether each of the following statements about ribosomes is true or false.

1. Ribosomes are composed of tRNA and protein. TrueFalse
2. During translation in eukaryotes, some ribosomes remain free in the cytoplasm while others attach to protein channels embedded in the RER. TrueFalse
3. During initiation of translation, the small ribosomal subunit joins to the mRNA and initiator rRNA, followed by the large ribosomal subunit. TrueFalse
4. When a ribosome first assembles on the mRNA, the initiator tRNA occupies the A site while the P and E sites are empty. TrueFalse
5. During translation, a charged tRNA first binds to the ribosome if its anticodon matches the codon in the E site. TrueFalse
6. A peptide bond forms between the amino acid attached to a tRNA in the A site and the growing polypeptide attached to a tRNA in the P site. TrueFalse
7. Uncharged tRNA molecules in the E site are ejected from the ribosome. TrueFalse
8. No more than 2 tRNA molecules are bound to a ribosome at any given time. TrueFalse
9. During translocation of the ribosome, tRNA molecules move from the P site, to the A site, to the E site, and are then ejected from the ribosome. TrueFalse
10. During translation, an amino acid attached to a tRNA in the A site is transferred to a growing polypeptide attached to a tRNA in the P site. TrueFalse

Explanation / Answer

. Ribosomes are composed of tRNA and protein. False
2. During translation in eukaryotes, some ribosomes remain free in the cytoplasm while others attach to protein channels embedded in the RER. True
3. During initiation of translation, the small ribosomal subunit joins to the mRNA and initiator rRNA, followed by the large ribosomal subunit. False
4. When a ribosome first assembles on the mRNA, the initiator tRNA occupies the A site while the P and E sites are empty. False

5. FALSE. The tRNA complex first binds to the A site, then moves to the P site, and is released at the E site. Anticodon should match with the codon in the A site.

6. A peptide bond forms between the amino acid attached to a tRNA in the A site and the growing polypeptide attached to a tRNA in the P site. True
7. Uncharged tRNA molecules in the E site are ejected from the ribosome. True
8. No more than 2 tRNA molecules are bound to a ribosome at any given time. False (Each ribosome contains three binding sites for tRNA molecules).

9. During translocation of the ribosome, tRNA molecules move from the P site, to the A site, to the E site, and are then ejected from the ribosome. True.
10. During translation, an amino acid attached to a tRNA in the A site is transferred to a growing polypeptide attached to a tRNA in the P site. False (the growing polypeptide chain is removed from the P site and attached to the A site).

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