1. The coalescence of mtDNA to a common female ancestor in this pedigree indicat
ID: 48164 • Letter: 1
Question
1. The coalescence of mtDNA to a common female ancestor in this pedigree indicates that she was the only woman alive at this time.
2. Individual I-4 did not contribute her mtDNA to the most recent generation.
3. Individuals I-3 and I-4 did not contribute any genetic material to the most recent generation.
4. The coalescence of Y chromosomal DNA to a common male ancestor in this pedigree indicates that he was the only man alive at this time.
5. Individual I-3 did not contribute his Y chromosomal DNA to the most recent generation.
6. The most recent common mtDNA and Y chromosomal DNA ancestors were one couple.
Aa Aa Y chromosome variants: Aa mtDNA variants: Aa Aa IV aa AaExplanation / Answer
The true statements are:
2. Individual I-4 did not contribute her mtDNA to the most recent generation. The most recent generation inherited their Y-chromosome from individual I-1 and mtDNA from individual I-6
5. Individual I-3 did not contribute his Y chromosomal DNA to the most recent generation. The most recent generation have Y-chromosome owned from individual I-1
The other statements are wrong due to the following reasons:
statement 1: The mitochondrial DNA of individual I-4 is inherited in two generations. Thus, the statement is wrong.
Statement 3: There is contribution of genetic material from these two individuals, but neither the Y-chromosome nor the mtDNA of these individuals is passed on to the recent generations
Statement 4: The Y chromosome of individual I-3 was inherited in two generations. Thus, the statement is wrong.
Statement 6: The most recent common mtDNA and Y chromosome contributors are individuals I-6 and I-1 respectively. They are not coupels.
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