The liver has the enzyme glucose-6-phosphate which catalyzes the removal of phos

Question

The liver has the enzyme glucose-6-phosphate which catalyzes the removal of phosphate from glucose-6-phosphate. Explain why this enzyme is not present in muscle tissues, but is liver specific. The liver has the enzyme glucose-6-phosphate which catalyzes the removal of phosphate from glucose-6-phosphate. Explain why this enzyme is not present in muscle tissues, but is liver specific. The liver has the enzyme glucose-6-phosphate which catalyzes the removal of phosphate from glucose-6-phosphate. Explain why this enzyme is not present in muscle tissues, but is liver specific.

Explanation / Answer

the step of removal of phosphate from glucose-6-phosphate is catalyzed by glucose-6-phosphate, which is the last stpe of gluconeogenesis or glycogenolysis. the presence of this enzyme is specific to liver or pancreas tissue and it also acts for sensing blood glucose level and feedback mechanism for insulin secretion.it also has important role when glucose levels are low during fasting or diabetic condition. the enzyme is helpful on homostasis of glucose and glycogen. the glycogen in the muscles cannot become available tothe rest of the body's cells due to its specific presencec as it cannot cross the sarcolemma unless it is dephosphorylated.

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