Glycolysis is the process by which energy is harvested from glucose by living th

Question

Glycolysis is the process by which energy is harvested from glucose by living things. Several of the reactions of glycolysis are thermodynamically unfavorable (nonspontaneous), but proceed when they are coupled with other reactions. (a) Which of these reactions is(are) unfavorable? Select all that apply. A. P_i + glucose rightarrow glucose-6-phosphate + H_2 O Delta G = 13.8 kJ/mol B. P_i + fructose - 6 - phosphate rightarrow fructose - 1,6 - bisphosphate + H_2 O C. ATP+ H_2 O rightarrow ADP+ P_i Delta G = -30.5 kJ/mol A B C (b) Which of these reactions can be coupled so that the overall reaction is favorable? Select all that apply. A and B A and C B and C (c) What is the net change in free energy if one set of reactions from part (b) is coupled so that the overall reaction is favorable? Delta G = (if you selected more than one pair of reactions in part (b), enter the net change for any one of your selected sets)

Explanation / Answer

a) Unfavoruable reactions have dG = +ve value

Hence answer is options A , B

b) when two reactions coupled we add their dG, so combination of A,C and   B,C gives us dG = -ve

hence these two are favourable

c) lets take A, C

dG = 13.8 KJ/mol - 30.5 KJ/mol

         = - 16.7 KJ/mol

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