Unlike steroid hormones, signaling molecules that are large and/or hydrophilic c

Question

Unlike steroid hormones, signaling molecules that are large and/or hydrophilic cannot pass through the cell's plasma membrane and therefore must bind extracellulary to receptor molecules in the plasma membrane. Two types of signal receptors embedded in the cell?s plasma membrane are G protein-coupled receptors and receptor tyrosine kinases. Classify each statement by whether it applies to G protein-coupled receptors only, receptor tyrosine kinases only, both receptors, or neither receptor. both receptors 1. involves GTP receptor tyrosine kinases 2. involves the phosphorylation of the receptor G protein-coupled . . . 3. receptor has enzymatic activity receptors 4. binding of the signaling molecule forms a dimer y receptor tyrosine kinases 5. Ligand-binding site is located on the extracellular side of the cell neither receptor 6. receptor is located in the plasma membrane 7. binding of the signaling molecule allows ions to flow through a channel in the y both receptors receptor receptor tyrosine kinases

Explanation / Answer

tyrosine kinase : involves the phosphorylation of the receptor.

receptor has enzymatic activity .

binding of the signalling molecule forms a dimer

ligand binding site is located on the extracellular side of the cell.

G protein coupled receptor :

involves GTP.

receptor is located on the plasma membrane .

binding of the signalling molecule allows ions to flow through a channel in the receptor.

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