If you had a mutant that was defective in the indicated component below, and cre

Question

If you had a mutant that was defective in the indicated component below, and created a merodiploid with a wild type copy of that same component, which scenario would allow replication of the mutant genome to still occur like normal (as if it were wild type)?

For example, a strain with a mutant DNA polymerase and an added copy of DNA polymerase. In this case, could replication still occur? Follow the same pattern for each additional component.

DNA polymerase

DNA ligase

Helicase

Topoisomerase

Centromere

Promoter DNA for DNA polymerase gene

Origin of replication

Single stranded binding protein

Multiple answers are possible.

Explanation / Answer

DNA polymerase: The presence of a merodiploid with the wildtype gene will cover the deficiency.

DNA ligase: The presence of a merodiploid with the wildtype gene will cover the deficiency.

Helicase: The presence of a merodiploid with the wildtype gene will cover the deficiency.

Topoisomerase: The presence of a merodiploid with the wildtype gene will cover the deficiency.

Centromere: Since the centromere is a part of a chromosome, it cannot be covered with the merodiploid.

Promoter DNA for DNA polymerase gene: The presence of a merodiploid with the wildtype gene will cover the deficiency.

Origin of replication: This deficiency cannot be covered.

Single stranded binding protein: The presence of a merodiploid with the wildtype gene will cover the deficiency.

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