16) Find the false statement a) DNA helicases serve to unwind the double helix b

Question

16) Find the false statement

a) DNA helicases serve to unwind the double helix

b) Single-stranded DNA binding proteins serve to prevent the double-helix from reforming

immediately

c) DNA polymerase III is the main DNA polymerase, and can be found synthesizing DNA at

both leading and lagging strands

d) DNA polymerase I also contains an exonuclease activity that can breaks down and removes

RNA and is one of the enzymes involved in completing DNA synthesis on the lagging strand

e) DNA replication involves replication forks that move along the DNA

f) The enzymes that replicate DNA assemble into a large complex called the replisome

g) DNA polymerases are able to catalyze the formation of dinucleotides from two nucleotide

monomers

h) Short RNA primers are synthesized by the DNA primase

i) DNA polymerases add new deoxyribonucleotides only at the 3

Explanation / Answer

a) True : DNA helicase move to the replication fork, and slowly opening and unwinding the DNA double helix.

b) True : Because single-stranded DNA bind to ssDNA and prevent the formation of DNA double helix and by this way maintaining the strand separation which facilitating the synthesis of the nascent strand.

c) True : DNA polymerase III is the main enzyme complex for prokaryotic involved DNA replication. DNA polymerase III synthesizes base pairs at a rate of around 1000 nucleotides per second.

d)

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