Domestic dogs vary greatly in adult size. All dog breeds have the IGF-1 gene cod

Question

Domestic dogs vary greatly in adult size. All dog breeds have the IGF-1 gene coding for a hormone which promotes
growth to adolescence. Scientists have discovered that all small dog breeds have an allele, called S, of another gene
close to IGF-1. The best hypothesis to explain the size range in dogs is that

A. IGF-1 is the only gene controlling growth in dogs.
B. the gene product of the S allele is a promoter of IGF-1.
C. large breeds cannot produce a transcript of the IGF-1 gene.
D. when S is translated its product inhibits IGF-1 gene expression.

Explanation / Answer

large breeds cannot produce a transcript of the IGF-1 gene

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