1. Two alleles of a gene code for exactly the same amino acid sequence and yet t

Question

1. Two alleles of a gene code for exactly the same amino acid sequence and yet the produce different proteins: explain how this can occur.

2. An extremely clever approach to using the lack of restriction point control against cancer cells is shown in your text (Kleinsmith) p28 figure 2.12. The main point of this that since cancer cells lack proper ____________________ they will enter the S phase when normal cells cannot because of ____________________.

3. RB prevent the cell from undergoing ______________ by binding to _________ which is a transcription factor .

4. The transcription factor to which RB bind controls _______________. RB become inactive when it is _________.

Explanation / Answer

1. Different copies of a gene do not always give exactly the same instructions

2. can't find figure

3. RB prevent the cell from undergoing S phase by binding to E2F which is a transcription factor

4.The transcription factor to which RB bind controls progression through each of the phases of the cell cycle. RB become inactive when it is phosphorylated by cdk.

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