The potential application of iPS cell technology for individualized medicine is

Question

The potential application of iPS cell technology for individualized medicine is best described by the following scenario:

A.

Fibroblasts from a Parkinson's disease patient are used to create iPS cells, which are then directed to differentiate into nervous tissue, which are then used to screen a variety of candidate drugs for the treatment of Parkinson's disease.

B.

Fibroblasts from a Parkinson's disease patient are used to create patient-specific iPS cells, which are then directed to differentiate into functional dopaminergic neurons, which are then introduced back into the brain of the original patient.

C.

Mouse fibroblasts are used to create iPS cells, which are then directed to differentiate into functional dopaminergic neurons, which are then introduced into the brains of Parkinson's disease patients.

D.

Somatic cell nuclear transfer is used to create functional dopaminergic neurons which are then introduced into the brains of Parkinson's disease patients.

E.

Cell fusion is used to create functional dopaminergic neurons which are then introduced into the brains of Parkinson's disease patients.

A.

Fibroblasts from a Parkinson's disease patient are used to create iPS cells, which are then directed to differentiate into nervous tissue, which are then used to screen a variety of candidate drugs for the treatment of Parkinson's disease.

B.

Fibroblasts from a Parkinson's disease patient are used to create patient-specific iPS cells, which are then directed to differentiate into functional dopaminergic neurons, which are then introduced back into the brain of the original patient.

C.

Mouse fibroblasts are used to create iPS cells, which are then directed to differentiate into functional dopaminergic neurons, which are then introduced into the brains of Parkinson's disease patients.

D.

Somatic cell nuclear transfer is used to create functional dopaminergic neurons which are then introduced into the brains of Parkinson's disease patients.

E.

Cell fusion is used to create functional dopaminergic neurons which are then introduced into the brains of Parkinson's disease patients.

Explanation / Answer

Answer:

D. Somatic cell nuclear transfer is used to create functional dopaminergic neurons which are then introduced into the brains of Parkinson's disease patients.

Lesions of the substantia nigra lead to the common and extremely severe disease of rigidity, akinesia, and
tremors known as Parkinson

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