2) Numerous Homo sapiens neanderthalensis sequences have been determined in the

Question

2) Numerous Homo sapiens neanderthalensis sequences have been determined in the past 10+ years - including a complete genome. Listed are the variable positions from an alignment of four Neandertal sequences (Nea1-Nea4) and a modern H. sapiens sequence (sap 1) and also the matrix of pairwise differences among these five sequences The variable positions (1-25): Please: (a) How many of the 25 variable nucleotide positions are informative for the parsimony method? Which are they? (b) Infer a phylogeny for these sequences, map the characters onto the tree and how many steps does it require?

Explanation / Answer

a) Nea 4, Nea 1

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