A.) What is the meaning of the term consensus sequence? What consensus sequences

Question

A.) What is the meaning of the term consensus sequence? What consensus sequences are important for a bacterial RNA polymerase to bind to a promoter? Describe the locations of consensus sequences within bacterial promoters. What are their functions?

B.) What is the consensus sequence of the following six DNA sequences?

A.) What is the meaning of the term consensus sequence? What consensus sequences are important for a bacterial RNA polymerase to bind to a promoter? Describe the locations of consensus sequences within bacterial promoters. What are their functions? B.) What is the consensus sequence of the following six DNA sequences? 12) What is the consensus sequence of the following six DNA sequences? GGCATTGACT GCCATTGTCA CGCATAGTCA GGAAAT GGGA GGCTTTGTCA GGCATAGTCA

Explanation / Answer

consensus sequence means is the calculated order of most frequent residues either nucleotide or amino acid. The consensus sequence important for RNA polymerase is -10 sequence called pribnow box which has the sequence of TATAAT and -35 sequence having TTGACA. the -10 and -35 regions are designated to reflect their approximate distance in nucleotides from the start site. TATAAT is used for binding of the alpha subunit of RNA polymerase to the promoter. strong promoter is havng TATAAT sequence which is required for tight binding which forms large number of transcripts.

the consensus is GGCATTGTCA

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