Antibiotics kill bacteria and can be an effective treatment for bacterial diseas

Question

Antibiotics kill bacteria and can be an effective treatment for bacterial diseases. Antibiotic resistance is an evolutionary response by the bacteria to an antibiotic, where bacteria are able to survive and increase in the population if they possess a mutation such that the antibiotic is not effective. Then, the antibiotic is less successful against that population of bacteria. The British government has called antibiotic resistance a major national risk. In this article, Antibiotics Target Gene Expression, the Chief Scientific Officer of ProCarta BioSystems, Michael McArthur, discusses a new antibiotic targeting gene expression. Answer the following four questions based on this article. Be sure to put your answers in your own words and number your answers. What type of molecule is their new antibiotic? What is the mechanism that the antibiotic uses to kill specific bacteria? What prevents the antibiotic from killing human cells? How did they describe how the antibiotic might enter the bacterial cell?

Explanation / Answer

1. the molecule is oligonucleotides switches

2. these are switches which act as gene regulators. they have sequence complementary to the DNA thus, inhibit transcription and in turn target certain genes within the bacteria, which are responsible for making the bacteria pathogenic. they can stop the infection

3. these oligontds are delivered within liposomes that target the bacteria specifically.

4. if the lipid encapsulation is designed such that it can represent membrane characters then it will allow bacteria to take up the drug

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