Programmed cell death, also called apoptosis, is a genetically controlled event
ID: 38165 • Letter: P
Question
Programmed cell death, also called apoptosis, is a genetically controlled event that helps shape organs and tissues during normal development. In the nematode C. elegans, normal development relies on three genes involved in programmed cell death, ced-3, ced-4, and ced-9.
In C. elegans, ced-3 and ced-4 initiate the genetic events that lead to programmed cell death (apoptosis). The expression of ced-3 and ced-4 are controlled by ced-9. The ced-9 gene acts as a binary switch in the genetic pathway controlling cell death, as shown in the diagram. . If ced-9 is active. ced-3 and ced-4 are repressed. allowing the cell to remain alive (and not undergo programmed cell death). . However, if ced-9 is inactive. ced-3 and ced-4 are expressed and initiate cell death. For each mutation described below, determine whether it would result in cell survival or cell death. Drag the terms to the appropriate blanks to complete the sentences. Terms can be used once, more than once, or not at all. Programmed cell death, also called apoptosis, is a genetically controlled event that helps shape organs and tissues during normal development. In the nematode C. elegans, normal development relies on three genes involved in programmed cell death, ced-3, ced-4, and ced-9.Explanation / Answer
Answer
1. Result in cell survival
2. Result in cell death
3. Result in cell death
4. Result in cell survival
5. Result in cell survival
6. Result in cell death
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