Glucagon is a hormone that is released when the level of glucose in the blood ge

Question

Glucagon is a hormone that is released when the level of glucose in the blood gets low. Through a G protein signaling pathway, glucagon, among a few different actions, promotes glycogenolysis to occur. Put the steps of the signal transduction pathway in order from the releasing of glucagon into the blood to the promotion of glycogenolysis.

*glucagon binds extracellulary to G protein-coupled receptor
*G protein releases GDP and binds GTP
*activated G protein activated adenylyl cylcase
*adenylate cyclase convert ATP to cAMP
*Cyclic AMP activates protein kinase A
*Phosphorylase kinase phosphorylates glycogen phosphorylase, an enzyme needed needed for glycogenolysis

Explanation / Answer

1.glucagon binds extracellulary to G protein-coupled receptor

2.G protein releases GDP and binds GTP

3.activated G protein activated adenylyl cylcase

4.adenylate cyclase convert ATP to cAMP

5.Cyclic AMP activates protein kinase A

6.Phosphorylase kinase phosphorylates glycogen phosphorylase, an enzyme needed needed for glycogenolysis

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