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The individual steps in the Michaelis-Menten enzyme mechanisminvolve all of the

ID: 3641 • Letter: T

Question

The individual steps in the Michaelis-Menten enzyme mechanisminvolve all of the following EXCEPT:



a. The rateconstant k-2 can be ignored since no P is present to convert backto S, when the initial velocity (Vo) is measured

b. k1 is the rateconstant for formation of the ES complex from E and S

c. The step in themechanism involving k2 is much faster than the step involving k1 /k -1

d. k2 is the rateconstant for the catalytic step in which S is converted to P in theactive site of the enzyme

e. k -1 is therate constant for dissociation of S from the ES complex

The individual steps in the Michaelis-Menten enzyme mechanisminvolve all of the following EXCEPT:



a. The rateconstant k-2 can be ignored since no P is present to convert backto S, when the initial velocity (Vo) is measured

b. k1 is the rateconstant for formation of the ES complex from E and S

c. The step in themechanism involving k2 is much faster than the step involving k1 /k -1

d. k2 is the rateconstant for the catalytic step in which S is converted to P in theactive site of the enzyme

e. k -1 is therate constant for dissociation of S from the ES complex

Explanation / Answer

c. The step in the mechanism involving k2 is much faster than the step involving k1 / k -1