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Question 1 1. Zane, a 26-year-old male, came upon a car accident and immediately

ID: 3524047 • Letter: Q

Question

Question 1 1. Zane, a 26-year-old male, came upon a car accident and immediately started to help the victims, who were pinned in their car. There was blood all over the scene and Zane acted without having any personal protective equipment. While helping the victims, he cut his arms in several places on the sharp metal and shards of glass. A few weeks later, he developed flu-like symptoms that persisted for several days. He went to his clinic and tested negative for influenza. Because of his recent exposure, Zane's doctor was suspicious of blood bome pathogens Which of the following disorders are blood-borne diseases? C HIV infection C Hepatitis A CCirrhosis Leukemia Question 2 1. Lab tests confirm the presence of HIV antibodies in Zane's blood. Briefly describe why there are antibodies present Question 3 1. Briefly define "autoimmunity" and "immunodeficiency" in your own words. Which of these conditions is Zane more likely to develop?

Explanation / Answer

1) a. HIV infection

Not b. Because hepatitis is transmitted through contaminated water, food and contact with fomites. Not c. and d. because both of them are non-contagious.

2)antibodies are generated by B-cells of our body upon getting exposed to the specific antigens. Since Jane was exposed to HIV infected blood of one of the victims during the accident, he acquired the virus into his blood through the cuts. This resulted in an immune response against the virus.

3)autoimmunity is a condition in which a person's immune system begins to generate antibodies against self antigens and hence attacks the body's own cells.

Immunodeficiency is a condition wherein a person's immune system is compromised and fails to generate an efficient immune response in order to fight an invasive attack by foreign bodies.

Jane is likely to develop immunodeficiency as the HIV virus would infect the T-cells (CD4+) cells hence preventing the activation of B-cells and hence antibody production is compromised.

4) as explained above T-cells decrease in number.

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