Match each description with its correct term: ions or small molecules that are n

Question

Match each description with its correct term:

ions or small molecules that are needed for activity of a specific enzyme

      [ Choose ]            lock and key model            induced fit model            turnover number            a metabolic pathway            allosteric inhibition            mass action            cofactors or coenzymes            an optimal pH      

a condition at which an enzyme exhibits peak activity

      [ Choose ]            lock and key model            induced fit model            turnover number            a metabolic pathway            allosteric inhibition            mass action            cofactors or coenzymes            an optimal pH      

a sequence of enzymatic reactions

      [ Choose ]            lock and key model            induced fit model            turnover number            a metabolic pathway            allosteric inhibition            mass action            cofactors or coenzymes            an optimal pH      

a final product of a metabolic pathway binding to an intermediate enzyme outside of its active site

      [ Choose ]            lock and key model            induced fit model            turnover number            a metabolic pathway            allosteric inhibition            mass action            cofactors or coenzymes            an optimal pH      

a reaction driven from high (substrate) to low (product) concentration

      [ Choose ]            lock and key model            induced fit model            turnover number            a metabolic pathway            allosteric inhibition            mass action            cofactors or coenzymes            an optimal pH      

Explanation / Answer

1. Ions or small molecules that are needed for activity of a specific enzyme

Ans:  cofactors or coenzymes

Cofactors are mostly metal ions tat assist enzymes during the catalysis of reactions.

Coenzymes are non-protein organic molecules,mostly derivatives of vitamins , they bind apoenzyme to proteins to form holoenzyme.

2. a condition at which an enzyme exhibits peak activity

Ans:  an optimal pH

An enzyme shows maximum activity over the specific pH range in which a molecule exists in its properly charged form and is called the optimum pH of the enzyme. Example: Most body fluids have pH values between 6 and 8.

3. a sequence of enzymatic reactions

Ans:  a metabolic pathway

A metabolic pathway is series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites and catalyzed by enzymes.

4. a final product of a metabolic pathway binding to an intermediate enzyme outside of its active site

Ans:  allosteric inhibition        

Allosteric inhibition / Negative allosteric modulation occur when binding of one ligand decreases the affinity for substrate at other sites. Ex: when 2,3-BPG binds to an allosteric site on Hb (Hemoglobin) leads to decreased affinity of all subunits for oxygen.   

5. a reaction driven from high (substrate) to low (product) concentration

Ans:  mass action

Law of mass action is rate of a chemical reaction, directly proportional to the product of the activities or concentrations of the reactants. Which is important for behaviors of solutions in dynamic equilibrium.

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