microbiology HIV. d. influenza. 36. CASE HISTORY hreeyear-old Molly was brought
ID: 3518297 • Letter: M
Question
microbiology
HIV. d. influenza. 36. CASE HISTORY hreeyear-old Molly was brought to the emergency department crying. She had a stiff neck and high ever (40° G or 104 F). Gram stain of her cerebrospinal fluid revealed Gram-positive cocci, generally in pairs The attending physician diagnosed Molly with meningitis and immediately prescribed intravenous ampicillin. Unfortunately, the child's condition worsened, so antibiotic treatment was changed to a third-generation cephalosporin (ceftriaxone). Molly began to improve within hours and was released after two days. A report from the clinical microbiology laboratory two days later identified the organism as Streptococcus pneumoniae. The report also included antibiotic susceptibility results, which revealed that this strain of S. pneumoniae was resistant to ampicillin b remained susceptible to cephalosporin The first antibiotic used to treat Molly, ampicillin, has activity against both Gram-negative a nd Gram-positive bacteria; however, the bacterium that made Mollyill was resistant t ribed, neither the type of agent nor its resistances were know Based on this information, which of the following is true? a. Ampicillin is a broad-spectrum antibiotic. b. Gram-positive bacteria are resistant to ampicillin, so it should be used only for Gram-negative infections. c. Molly's illness should have been treated with a narrow-spectrum antibiotic. d. Molly's infection is resistant to a broad variety of antibioticsExplanation / Answer
Answer A
Ampicillin is gram is the broad-spectrum antibiotic.
Normal, it produces the action against both gram-positive and gram-negative bacteria.prevousely for the treatment of meningitis, ampicillin or penicillins are useful but later rising the problem of resistance against penicillins due to genetic mutations of the organism. but it is susceptible to third generation cephalosporins.
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