In 1991 , your client, a 22 year old male, was 72” (1.83 m) tall and weighed 175
ID: 3517039 • Letter: I
Question
In 1991 , your client, a 22 year old male, was 72” (1.83 m) tall and weighed 175 lbs. (79.55 kg) with 15% body fat as measured by DEXA. Biopsy from various sub cutaneous depots revealed an average adipocye triacylglycerol mass of 0.5 ?g. What is the estimated number of adipocytes?
A. 15.5B
B. 20.2B
C. 23.8B
D. 35.5B
E. 40.5B
In 2018 , he is now 47 years old, he is completely sedentary, weighs 300 lbs. (136.4 kg) and has 35% body fat. If the triacylglycerol content in the average adipocyte is exactly 1 mg, what is his current estimated number of adipocytes?
A. 19.9B
B. 23.8B
C. 39.6B
D. 47.7B
E. 65.4B
He seeks your advice on improving his health and fitness. A baseline assessment reveals his daily energy intake is 2800 kcal (35% fat; 50% CHO, 15% protein) with a daily estimat ed energy expenditure of 2700 kcal (REE+TEF). You plan a program which includes 2550 kcal diet (25% fat; 60% CHO; 15% protein) and adds 350 exercise kcal·day - 1 (total daily energy expenditure=3050 kcal). Each week, he will r eport his weight and you will provide an adjusted caloric intake to maintain the energy balance of - 500 kcal·day - 1 . In theory, how much total weight and fat weight has he lost in 12 weeks?
Week
1
2
3
4
5
6
7
8
9
10
11
12
% protein·lost lb - 1
5
5
10
10
15
15
15
12.5
12.5
10
10
10
% water·lost lb - 1
70
45
20
20
5
5
5
0
0
0
0
0
% fat·lost lb - 1
25
50
70
70
80
80
80
87.5
87.5
90
90
90
Total %
100
100
100
100
100
100
100
100
100
100
100
100
A. ~12 lbs total / ~12 lbs fat
B. ~12 lbs total / ~9 lbs fat
C. ~24 lbs total / ~24 lbs fat
D. ~24 lbs total / ~12 lbs fat
Which mode of exercise is likely to promote the greatest caloric expenditure in your client?
A. Weight lifting
B. Flexibility
C. Swimming
D. Cycle ergometer exercise
E. Brisk walking exercise
Based on your answers in the questions above , what is the estimated number of adipocytes after 12 weeks of modified diet and exercise?
A. 19.9B
B. 23.8B
C. 3 9.6B
D. 47.7B
E. 65.4B
What is the estimated fat content per adipocyte after 4 weeks of modified diet and exercise?
A. 1.00 mg
B. 0.91mg
C. 0.87 mg
D. 0.75 mg
E. 0.67 mg
Week
1
2
3
4
5
6
7
8
9
10
11
12
% protein·lost lb - 1
5
5
10
10
15
15
15
12.5
12.5
10
10
10
% water·lost lb - 1
70
45
20
20
5
5
5
0
0
0
0
0
% fat·lost lb - 1
25
50
70
70
80
80
80
87.5
87.5
90
90
90
Total %
100
100
100
100
100
100
100
100
100
100
100
100
Explanation / Answer
1. Since 15% of the person's body weight is composed of fat, the total weight of fat = 15% of body weight of the person = 15/100 × 79.55 Kg
= 11.9325 Kg or 11932500mg
Average weight of adipocyte is 0.5 mg
Hence, number of adipocytes = total weight of fat / average weight of adipocyte = 11932500/0.5 = 23.8 B
Answer = c) 23.8 B
2. Since 35% of his body weight is fat, total weight of fat = 35/100 * 136.4 Kg = 47.74 Kg = 47740000mg
Number of adipocytes = total weight of fat/ average weight of adipocyte
= 47740000/1 = 47.7B
Answer: d)47.7 B
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