Myosin is the motor protein underlying muscle contraction. A muscle contracts be
ID: 3514871 • Letter: M
Question
Myosin is the motor protein underlying muscle contraction. A muscle contracts because of the combined action of trillions of individual myosin molecules. In this problem, you will characterize the molecular mechanism behind muscle contraction.
The following table lists five events that a given myosin molecule will execute immediately following the propagation of an action potential along the T-tubules of a muscle fiber. Order these events, with 1 belong the first event and 5 being the last.
Event:
Ca2+ binds to troponin. ------
The myosin head releases ADP and Pi , causing itself to bend into a more upright position. --------
The myosin head binds, forming a cross-bridge, to the thin filament, using the energy from hydrolyzing its bound molecule of ATP. ------
The cross-bridge breaks; The myosin head binds ATP and releases itself from the thin filament. * ----------
The sarcoplasmic reticulum releases Ca2+ into the cytosol. --------
Explanation / Answer
1.The sarcoplasmic reticulum releases Ca2+ into cytosol.
2.Ca2+ binds to troponin.
3.The myosin head binds,forming a crossbridge ,to THIN filaments using the energy from hydrolysing its bound molecule of TAP.
4.The myosin head releases ADO and PI causing itself to bend into more upright position .
5.The cross bridge breaks ;The myosin head binds TAP and releases itself from thin filament.
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