NOTE: EXPLAIN REASONING FOR EACH ANSWER Healthy kidneys contribute in several wa

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NOTE: EXPLAIN REASONING FOR EACH ANSWER

Healthy kidneys contribute in several ways to the regulation of normal Ca2+ concentration in the extracellular fluid. In the advanced stages of chronic kidney disease, these mechanisms can fail, with consequent disruption of calcium balance. Which one of the following would you least expect in a person with untreated chronic kidney disease? O a reduced synthesis of calcitriol Ob high plasma phosphate concentration O reduced secreton of parathyrold hormone O d. decreased absorption of dietary Ca2+ from the intestine

Explanation / Answer

In CKD the reduce secretion of parathyroid hormone can be least expected as in CKD as the disease process, it seems clinically that to maintain neutral calcium balance throughout the stages of CKD, because of calcium deficiency could lead to excessive bone loss and secondary hyperparathyroidism that is abnormally increase of parathyroid hormone and calcium excess could accelerate vascular and soft tissue calcification. Balance studies suggest that patients are, on average, in neutral calcium balance while consuming 800–1000 mg/day. This is therefore a sensible starting point for dietary calcium intake recommendations

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