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Please answer all parts: a.) Describe activation steps for the GH receptor follo

ID: 3512265 • Letter: P

Question

Please answer all parts:

a.) Describe activation steps for the GH receptor following hormone binding.

b.) What kind of changes will occur in the pituitary following thyrodectomy?

c.) What is the effect of TSH following a thyrodectomy?

d.) Which of the listed organs are endocrine glands?

Liver

Pituitary

Thyroid

Kidney

Adrenal

2.)

Concerning endocrine regulation of water homeostasis which one is FALSE?

            A.        During dehydration, antidiuretic hormone increases permeability of the collecting ducts to water, resulting in the concentration of urine.

            B.        Loss of blood will cause vasopressin release

C.        Vasopressin receptor activation is necessary for the increase of water resorption.

            D.        Pituitary oxytocin acts on distal tubules to increase water resorption.

            E.         Hormonally-regulated insertion of aquaporin is required for the concentration of urine.           

Explanation / Answer

a) Binding of growth hormone to the GH receptor leads to reorientation of a pre-assembled receptor dimer
The activation of an intra- and intercellular signal transduction pathway leading to growth.

C) TSH increases following thyroidectomy.

d) pituitary, thyroid, adrenal

2) D. Pituitary oxytocin acts on the uterus and facilitates its contraction during childbirth.also helps in lactation.

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