NOTE: Answer are in parantheses, EXPLAIN THE REASONING TO WHY chosen answer is c

Question

NOTE: Answer are in parantheses, EXPLAIN THE REASONING TO WHY chosen answer is correct and the others are incorrect

8 pts. 2. The diagram below shows the cross-bridge cycle of skeletal muscle as a set of four reactions (arbitrarily numbered reactions 1-4) in which the reactants change between 4 states (arbitrarily numbered states 1-4). Familiarize yourself with this depiction of the cross-bridge cycle, and then answer the following 4 questions (state 3) AM ADPP reaction1 reaction 2 (state 2) A M.ATP A-M ADPPi (state 4) Pi reaction 4 reaction 3 ATP ADP A-M KEY: X-Y high affinity binding between X&Y; (state 1) x - Y low affinity binding between X&Y; X Y no binding between X&Y;

Explanation / Answer

3.reaction 3:Myosin binds to actin and the powerstroke occurs. Initial weak binding releases inorganic phosphate. Stronger binding triggers the powerstroke and the release of ADP. The powerstroke involves the return of the myosin head to its low-energy conformation. The powerstroke generates force, pulling the thin filament toward the center of the sarcomere. Binding of another ATP molecule causes dissociation of myosin from actin and the cycle repeats itself.

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