Batrachotoxin, a toxin from the poison dart frog, was used historically for hunt

Question

Batrachotoxin, a toxin from the poison dart frog, was used historically for hunting on the end of a dart to paralyze prey. This toxin selectively binds sodium (Na+) voltage-gated channels causing a conformational change that decreases the voltage required for channel opening, increases the permeability of the channel to sodium and calcium, and prolongs the open state of the channel.

What does “decreasing the voltage required for channel opening” mean about the change in voltage required to cause opening of the channel? Choose ALL that apply. (2.5 points)

a) It takes less depolarization to open and will now open at a more positive value.

b) It takes more depolarization and will now open at a more negative value.

c) Threshold has changed.

d) It takes less depolarization to open and will now open at a more negative value.

e) It takes more depolarization and will now open at a more positive value.

Explanation / Answer

Following are the correct answers:

c) Threshold has changed.

d) It takes less depolarization to open and will now open at a more negative value.

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