Please select the best option for each of the following parts. Part A. The main

ID: 3511326 • Letter: P

Question

Please select the best option for each of the following parts.

Part A. The main function of RyR1 is to:

a) inhibit the DHPR

b) translocate Ca2+ from the sarcoplasm into the sarcoplasmic reticulum (SR)

c) release Ca2+ from the SR into the sarcoplasm

d) allow Ca2+ entry from the extracellular space into the sarcoplasm

e) sense sarcolemma depolarization and activate the DHPR

Part B. The main membrane protein inhibitor of SERCA2a in the heart ventricle is:

a) phospholamban (PLB)

b) sarcolipin

c) FKBP12.0

d) calmodulin

e) PKA

Part C. The main membrane protein inhibitor of SERCA2a in the heart atrium is:

a) phospholamban (PLB)

b) sarcolipin

c) FKBP12.6

d) CaMKII

e) PKA

Part A

C)release Ca2+ from the SR into the sarcoplasm

Part b

A)Phospholamban(PLB)

Part c

B) sarcolipin

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